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One possible explanation is that low serum vitamin B12 levels would trap folate as 5-methyltetrahydrofolate, prevent the generation of methionine from homocysteine, and therefore reduce protein synthesis and lean tissue deposition

Drenching in that moment increases the risk of liquid entering the lungs, which can lead to aspiration pneumonia

For pull-downs, we used two antibodies: against the full phospho-motif sequence of PKD LxRxx[S*/T*] and antibody against part of the PKD phospho-motif sequence Rxx[S*/T*]

The most common concentrations include 2.5mg/mL (typically in smaller 1 mL vials containing 2.5 mg total), 5mg/mL (in 1 mL vials containing 5 mg total or 2 mL vials containing 10 mg total), and occasionally higher concentrations for patients on maintenance doses

Distinguishing between them helps determine whether a medication adjustment is truly needed