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the LOC (Lead Optimized Compound) library is composed of 9,517 compounds selected from a starting pool of 3,372,615 compounds available through a variety of commercial libraries (Asinex, Moscow, Russia

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Two CpG sites in predicted PER1 enhancer regions and one CpG site in the CRY1 promoter region were found to be significantly hypermethylated in sleep-deprived adipose tissue samples