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Liver Detoxification: Concentrated in the liver, glutathione binds to toxins and aids in their removal from the body, detoxifying the liver and helping manage infections like fatty liver disease

Systemic metabolic alterations and their relationship to neuropsychiatric symptomatology PAIS, including long COVID, as well as CFS and IMD, share the characteristic of systemic metabolic disturbances, which may be a sign of underlying multi-organ inflammation and exhaustion [31], and consequently may contribute to neuropsychiatric symptomatology, as many metabolites can cross the bloodbrain barrier (BBB) [30, 58] (e.g., short chain fatty acids (SCFAs) derived from the gut microbiota such as acetate [40], amino acids such as tryptophan [52] and also carnitine/acetylcarnitine can cross the BBB via transporters [59])

So if you happen to be a vegetarian, or a vegan, its a safe bet you are not getting enough B12 unless you supplement

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Research indicates that mitochondrial dysfunction is one of the initiating factors of axonal degeneration