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its ability to eradicate biofilms appears due to the fact that it can kill bacteria regardless of growth state S

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Notably, the COF nanoparticles remain off in normal tissues, with both fluorescence and PDT effects quenched, but are selectively switched on in the hypoxic tumor environment, producing strong fluorescent signals and ROS generation ( Figure 13B )

Kolb H, Kempf K, Rhling M, Lenzen-Schulte M, Schloot NC, Martin S