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Donelson, R., Grant, W., Kamps, C., & Medcalf, R

#Organoids #ISoOR #ClinicalTranslation #PrecisionMedicine #PersonalizedMedicine #DrugDiscovery #DiseaseModeling #Biobanking #RegenerativeMedicine #Standardization #QualityManagement #BiomedicalResearch #OrganoidResearch To view or add a comment, sign in Decoding STAT6 Inhibition: A Masterclass in SBDD, Allostery, and the Danger of Leaky Inhibitors Just had the opportunity to deep-dive into an incredibly rich pharmacology dataset from ICE Bioscience in vitro assay validation for #STAT6 inhibitor profiling

In patients without confirmatory evidence of bacterial infection at 48 h, a PCT level below 1.0 g/L (in conjunction with a CRP level below 4 mg/dL) could be safely used to exclude the notion that clinical improvement was attributable to antibiotic treatment of an unidentified bacterial infection such that it would be appropriate to discontinue further antibiotics