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During sepsis, immune cells such as neutrophils and macrophages are rapidly activated in response to microbial invasion, releasing large amounts of ROS, including superoxide anion (O 2 ), hydrogen peroxide (H 2 O 2 ), and hydroxyl radicals (OH ), as part of the hosts antimicrobial arsenal (Di Meo et al., 2016)

[DOI] [PMC free article] [PubMed] [Google Scholar] 110.Bodmer W.F., Bailey C.J., Bodmer J., Bussey H.J., Ellis A., Gorman P., Lucibello F.C., Murday V.A., Rider S.H., Scambler P., et al