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bioRxiv (2023)

Torres Delgado, S

Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation

Each works independently without concern about blood flow interference

3.5 Mitochondrial DNA mutations and oxidative damage Each mitochondrion contains multiple copies of mitochondrial DNA (mtDNA), which is particularly susceptible to oxidative damage and somatic mutations due to its close proximity to the electron transport chain (56)