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221,222 In humans, cardiomyopathy has been observed in individuals with mutations in the synthesis of cytochrome c oxidase 2 (SCO2), a chaperone involved in trafficking Cu to cytochrome c oxidase (COX)

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Patel, R., & Singh, A

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Previous studies have shown that GSH content decreases after APAP overdose in animal livers (Jaeschke, 1990

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This is supported by a calculated 38 partition coefficient of 5.57 for the three hydrophobic sidechains of the N-terminal tail

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