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While lifestyle changes and medication can often provide relief, some cases may require surgical intervention

The safest approach is to keep it occasional, not a daily habit

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Additionally, metformin modulates immune function and inhibits excessive inflammation, such as by reducing levels of pro-inflammatory cytokines like IL-6 and TNF-, thereby alleviating cytokine storm-induced insulin resistance (141, 142)

in 1986, treatment with cyclosporin resulted in complete or partial diabetic remission during the treatment course, but the disease relapsed when cyclosporine was stopped [40]