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Many heavy metals such as mercury and lead are eliminated as GSH conjugates to prevent their irreversible binding to SH groups of many enzymes, including many membrane ATPase

Pharmaceutics 13 , 1042 (2021)

Excess ROS can damage all major cellular constituents (DNA, proteins, and lipids) and even lead to cell death, apoptosis, hypertrophy, fibrosis, and contractile dysfunction in the myocardium [8, 11]