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These results suggest that GGCT knockdown can significantly inhibit tumor growth and reduce GSH production and that the addition of the ROS inhibitor NAC can significantly rescue this effect

1 (download XLSX Statistical source data for Fig

This accumulation of senescent cells has been linked to several age-related diseases, including cardiovascular disease, osteoarthritis, and neurodegeneration [232]

Moreover, the AMD group displayed a significant increase in Escherichia-Shigella at the genus level compared with that seen in the control group, whereas the proportions of Blautia and Anaerostipes were lower (Zhang et al., 2023)