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Description

The composition of immune cell populations as well as their effector functions like pathogen clearance or phagocytosis changes during the process of aging, which is delineated for instance by an increased number of memory T cells compared to nave T cells due to thymus shrinkage, hence the loss of lymphoid tissue [11, 14, 15]

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Chin Med 18(1):138

This integrative perspective supports the notion that persistent disruption of metabolic, immune, and nutritional signaling may sustain the ASD phenotype