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doi: 10.1002/pbc.24784 Ekabe, C., Kehbila, J., Abanda, M., Kadia, B., Sama, C., & Monekosso, G

Their lipophilic nature favors corneal absorption, but nanoencapsulation ensures sustained release, reduces local irritation, and improves ocular pharmacokinetics (Mishra et al., 2021)

The duration of the trial was three years with 3862 patients exposed to Reclast and 3852 patients exposed to placebo administered once annually as a single 5 mg dose in 100 mL solution infused over at least 15 minutes, for a total of three doses