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Tau and neuroinflammation in Alzheimers disease: interplay mechanisms and clinical translation

Patient acceptability of a novel upper nasal delivery system for dihydroergotamine mesylate using the Precision Olfactory Delivery (POD) device results from the open-label STOP 301 trial

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Herein, any computer record for either prescribed medication (eg PPI) or prescribed supplementation (eg B12) within the 12 months leading up to the reference B12 test date notwithstanding the mode of delivery or duration of use within that year was considered positive for use

Injectable hair protocol: Dose: 1-2mg daily Frequency: Daily or 5 days weekly Duration: 16-24 weeks minimum (longer than anti-aging protocols) Cycle: 8 weeks on, 4 weeks off, repeat Topical scalp protocol: Concentration: 0.5% solution Application: 1-2ml to thinning areas twice daily Duration: 6+ months for meaningful assessment Technique: Apply to clean, dry scalp