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Additionally, markers of lipid peroxidation, such as MDA and 4-hydroxynonenal (4-HNE), showed no change

An additional strong positive peak appeared at a position expected to be occupied by the TNB moiety of the dead-end complex

[DOI] [PubMed] [Google Scholar] 98.Schmeisser K., Mansfeld J., Kuhlow D., Weimer S., Priebe S., Heiland I., Birringer M., Groth M., Segref A., Kanfi Y., et al

Phenolic metabolites can be classified into insoluble, cell wall-binding substances such as condensed tannins, lignin, and hydroxamic acid

When the committee lacks the technical depth to assess a novel product, the apparent speed advantage disappears, and the trial belongs in the CTA scheme regardless of how the sponsor would prefer to file it (TGA, 2024)