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Deep Dive into Its Origins and Development It was first created in research settings in order to investigate the metabolic pathways connected to age-related metabolic disorders and obesity

however, no case of ECL cell carcinoids, dysplasia, or neoplasia has been found in these patients [see Nonclinical Toxicology (13.1)] In over 1,000 patients treated with oral esomeprazole (10 mg, 20 mg or 40 mg/day) for up to 12 months, the prevalence of ECL cell hyperplasia increased with time and dose