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Description

In addition, kynurenine reduces the cytotoxicity of NK cells by inhibiting NK cell-activating receptors NKp46 and NKG2D 39

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XuSWaddellJZhuWShiDMarshallADMcKennaMCet al

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First, the historical absence of a globally unified definition of rare diseases constrained our study scope to the top ten rare diseases with the highest R&D activity, which may not fully represent the broader spectrum of rare disease research