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Reductions in the mitochondrial enzyme alpha-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental

When youre knocking back more than what your liver can handle within an hour, that excess ends up coursing through your bloodstream, leading to intoxication

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Ferroptosis has emerged as a pivotal mechanism of hepatocellular injury in MASLD, particularly in the setting of OxE, lipid peroxidation, and iron dysregulation