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Numerous proteins related to neurodegeneration possess CMA targeting sequences, including leucine-rich repeat kinase 2 (LRRK2) (167), ubiquitin C-terminal hydrolase isozyme L1 (UCH-L1) (168), -synuclein and microtubule-associated protein t (TAU)

Luciferase activity in cells expressing only IFN- reporter or ISRE reporter and Renilla plasmids was measured as a control

A: EveryDrop Water Filter 1 is compatible with various refrigerator models and removes contaminants like chlorine, lead, and pesticides

doi: 10.1146/annurev-cellbio-092910-154005 108 KlionskyDJSchulmanBA

Unfortunately, the CBS mutation doesnt know how to discriminate