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7 days) alleviates acute ethanol-induced hepatotoxicity in male C57BL/6JNifdc mice in a dose-dependent manner by reducing hepatic enzyme release, restoring hepatic antioxidant levels, alleviating histopathological damage, and inhibiting inflammatory signaling pathways [9]

Modern studies have reported that the protein-free Guang-Pheretima decoction (PF-GPD) can inhibit the release of inflammatory factors IL-1 and IL-6, regulate the homeostasis of microcirculation, and play an important role in the intervention of HACE pathology (Sun et al., 2019)

These findings are documented but derive predominantly from animal studies and should be interpreted accordingly