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[17] However, no large-scale, controlled trials have evaluated the efficacy or safety of ALA for pregnant patients, and thus there is insufficient evidence to consider it definitively safe

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Notably, a recent study reported that inhibition or activation of NLRP3 results in reduced or enhanced vascular SMC calcification, respectively

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A randomized placebo-controlled pilot trial shows that intranasal vasopressin improves social deficits in children with autism