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Their study in male mice and macaques demonstrated that IMA-1 disrupts the arachidonate 12-lipoxygenaseacetyl-CoA carboxylase 1 interaction, thereby treating NAFLD without inducing hyperlipidemia [74]

These findings suggest that autophagy is involved in several key pathologic aspects of RA, including pannus formation, synovial inflammation, and bone destruction

10.1007/s00394-019-01933-6 115

To learn more on the consequences of Stard7 deficiency in Wnt-driven tumor initiation on transcriptional reprogramming, we conducted RNA Sequencing experiments combined with GSEA with intestinal tumors from both Apc +/Min /Stard7 IEC and Apc +/Min /Stard7 Lox/lox mice