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Toxicity of benzyl alcohol in adult and neonatal mice

Subsequent studies reveal that RIPK1 and RIPK3 (receptor interacting serine/threonine kinase 3) are key upstream kinases that initiate necroptosis through the phosphorylation of executor protein MLKL (mixed lineage kinase domain like pseudokinase) by multiple regulators [112]

Jung DJ, Park JH, Jang JH, Ky L

At the same time, Trx (along with GSH) helps to buffer excess ROS generated by cell signaling or viral proteins, thereby protecting infected cells from oxidative stress-induced apoptosis