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10.1371/journal.pgen.1000004 PLoS Genet

[DOI] [PMC free article] [PubMed] [Google Scholar] Dorman DC, Moulin FJ, McManus BE, Mahle KC, James RA, Struve MF

Therefore, an amplification loop sustaining mitochondrial dysfunction in APAP-mediated hepatotoxicity has been suggested, involving two hits

A controlled trial published in the Journal of Clinical Oncology found that IV glutathione reduced neurotoxicity in patients receiving cisplatin chemotherapy without interfering with treatment efficacy