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J Clin Med 9:2359

It has been shown that reduced synaptic activity induced by sensory deprivation in young, but not adult animals, produces specific reductions in the number of perisomatic inhibitory synapses on cortical excitatory cells, unmasking a regulatory role of neuronal activity in determining the density of inhibitory cell contacts in this specific cellular compartment (Jiao et al., 2006)

In turn, the QMP substitutions improved the PK properties of a recombinant version of the GLP-1 albumin fusion albiglutide, irrespective of the presence of L585