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Ophthalmic diseases Severe acute and chronic allergic and inflammatory processes involving the eye, such as: Herpes zoster ophthalmicus Iritis, iridocyclitis Chorioretinitis Diffuse posterior uveitis and choroiditis Optic neuritis Sympathetic ophthalmia Anterior segment inflammation Allergic conjunctivitis Allergic corneal marginal ulcers Keratitis 7

This distinction matters because treatments targeting inflammation alone may provide only temporary relief without addressing the underlying tissue damage

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This dose level also showed the greatest total fat mass reduction in the body composition substudy, with participants losing an average of 21.6kg of pure fat mass compared to placebo