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Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer

18 The nutrients in the tumor microenvironment (TME) largely regulate tumor cell and immune cell metabolism

Chua, An Pan, Woon-Puay Koh The Journal of nutrition, health and aging.2025

However, this phase III trial was criticized for its small sample size, short duration, and high rate of patient dropout (De La Rubia et al., An open-label dose-escalation trial found administering another antioxidant and cofactor in the ETC, coenzyme Q10 (CoQ10

Overall, the readily prepared Cu-DMSA-HA NPs exhibit robust catalytic activity and tumor specificity, highlighting their strong potential for clinical translation in nanocatalytic cancer therapy