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dihexa clinical trial 2025

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Cells 18 ChangL.HuY.FuY.ZhouT.YouJ.DuJ.et al (2019)

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NCT04982575

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That approval status is a hard regulatory fact, and it is the single biggest reason a CagriSema-versus-tirzepatide comparison is not a comparison of equals: one product has cleared a full regulatory efficacy-and-safety review, and the other has not yet

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The overall impression from available evidence is that DSIP appears reasonably well-tolerated with a low incidence of serious adverse effects in the populations and contexts studied, but significant gaps in safety knowledge remain, particularly regarding long-term use, use in specific populations (elderly, children, those with comorbidities), and comprehensive toxicology assessment meeting modern pharmaceutical standards

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