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The C-terminal redox centre of hTrxR1, located on a flexible arm, has been expected to act as an electron shuttle between the buried N-terminal dithiol and the substrate 16,24

For studies that require the peptide to remain stable in a solution for an extended period, or for oral applications where it needs to survive the harsh environment of the GI tract, the arginine salt form presents a clear advantage

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The assignment is made by means of the relative migration times