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Author contributions MP, MM, and DP-S designed the study, performed experiments, analyzed data, prepared figures, and wrote the manuscript

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We monitored levels of antibodies against LCMV Cl13 glycoprotein 1 (Gp1) by ELISA at various time points after infection and observed that both early (IgM) and late (IgG) responses were undetectable in serum of infected mutant mice, in contrast to infected controls (Fig

It was suggested that Casiopeinas might alter levels of cellular 7-glutamyl-cyste-inyl-glicine (GSH, also known as tripeptide glutathione) by redox reactions which both generate and cause the over-production of free radical species, leading to mitochondrial dysfunction and cell death