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& Wu, D

Fibroids display an anti-angiogenic gene expression profile when compared with adjacent myometrium

This is because HGF has the ability to blunt inflammation in adipose tissue, by increasing M2 macrophage polarization, and consequently augmenting the expression of IL-10, both of which are positively associated with insulin sensitivity (see Figure 4)

In addition to increasing the generation of superoxide anions, hydrogen peroxide, and other peroxides, homocysteine may thus decrease the cellular ability to detoxify peroxides, especially hydrogen peroxide

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