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22 It is apparent that glutathione is a critical compound in maintaining health and glutathione deficiency and has been linked to numerous pathological conditions including, cancer, neurodegenerative disorders, cystic fibrosis, HIV, and aging

Intriguingly, two other Tdf proteins are present in pathogenic but in none of the commensal Neisseria species, TdfF and TdfG (Marri et al., 2010), suggesting a key role in virulence