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Black tea is prepared by full fermentation of Camellia sinensis leaves, resulting in the formation of oxidized and polymerized chemical compounds that are responsible for the distinct flavors and aromas [57, 58]

The latest research shows that berberine significantly decreases the expression of GFAP in the Alzheimers disease mice hippocampus, indicating berberine inhibits the overexpression of astrocytes in Alzheimers disease mice