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Int J Epidemiol 47:1314g

A deficiency may lead to irritability, concentration problems, or feelings of anxiety and depression

Discovering that low B12 is contributing to your mood doesn't mean you should adjust medications on your own

In rabbits, omeprazole in a dose range of 6.9 to 69.1 mg/kg/day (about 3.4 to 34 times an oral human dose of 40 mg on a body surface area basis) administered during organogenesis produced dose-related increases in embryo-lethality, fetal resorptions, and pregnancy disruptions