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Add TEV protease at a protease to target protein ratio of 1:100 (w/w) or 10,000 unit (1 mg) TEV protease to 100 mg of target protein

The Mantel-Haenszel fixed-effects model was used for the overall calculation of the OR, 95% CI and P-value calculations

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In addition, according to bioinformatics data, the ferroptosis-related factor APOE4 may be closely related to m6A methylation regulators in the brain tissue of AD patients (METTL3, METTL16, YTHDC2, and LRPPRC) (Du et al., 2021)

A total of 20,000 events were acquired and three replicates were used per experimental condition