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if anything is out of the ordinary, the physician is called in, the injection is abandoned, and a higher level E/M is reported

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doi: 10.1007/s10620-008-0271-5, PMID: [DOI] [PubMed] [Google Scholar] 13.Koplay M, Gulcan E, Ozkan F

Comprehensive safety studies spanning six months in rats (up to 100 mg/kg/day) and nine months in cynomolgus monkeys (up to 50 mg/kg/day) revealed no adverse findings, with NOAEL reaching the highest applied dosages

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