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Intramuscular Administration When used intramuscularly, ME 12 Injection should not be repeatedly injected at the same place

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34 Notably, buprenorphine maintenance treatment remains superior to detoxification alone in reducing illicit opioid use and increasing treatment retention

History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy