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This transporter maintains the dynamic equilibrium between extracellular cystine and intracellular glutamate by importing cystine while exporting glutamate at a 1:1 ratio (Jiang and Sun, 2024)

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AOD9604 and Safety Pharmacology Research A conventional Ames test showed no significant mutation rate increase for AOD9604 at up to 2,000 g/plate, with no clastogenic effects observed in CHO-cell chromosome aberration assays

In fact, in the case of lysozyme, the rapid glutathionylation of Cys94 stops completely the deleterious aggregation at pH 7.4 2 , while the glutathionylation of Cys1 in rChTg at this pH could not be detected due to a too fast protein aggregation (data not shown)