2026;4:1010132 DOI: Received: July 20, 2025 Accepted: March 18, 2026 Published: April 13, 2026 Academic Editor: Amnart Poapolathep, Kasetsart University, Thailand The article belongs to the special issue Neuroprotective Potential of Natural Products from Foods Aim: This study evaluated the comparative effects of commonly consumed artificial and natural sweeteners on cognitive function, neurotransmitter-related enzyme activities, and oxidative stress status in the brains of Wistar rats to elucidate their potential neurotoxic or neuroprotective properties under sub-chronic dietary exposure
In a rat model of ethylene glycol-induced calcium oxalate urolithiasis, BBR not only prevented and dissolved tubular crystal deposits but also significantly preserved renal function and mitigated oxidative stress
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When glucose levels are limited, ketone bodies generated in the liver and lactate derived from exercising skeletal muscle can also become important energy substrates for the brain
Concurrently, non-redox effects of NAD + , where NAD + transport, biosynthesis, and catabolism enable diverse roles in the regulation of energy transduction, in cell signaling, as a post-translational modifier, and as an epigenetic mediator have become apparent (3)
