foxo4 dri human trial senolytic Molecular modelling of the FOXO4-TP53 interaction to design peptides for the elimination of senescent cancer cells The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI alleviates age related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice Aging Peptide Inhibitors Targeting FOXO4 p53 Interactions and Inducing Senescent Cancer Cell specific Apoptosis Journal of Medicinal Chemistry Cellular senescence and senolytics: the path to the clinic Nature Medicine FOXO4 DRI: Human Trial Status, Cancer Research & Senolytic Data
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