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Subsequently, following irradiation, only the radiation resistant HIF1 KO cells further enhanced ser/gly metabolism, increasing AMP/ATP and GSH/GSSG (oxidized GSH) ratios, whereas HIF2 KO cells failed to adapt and accumulated oxidative stress

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These solutions were then fully mixed at room temperature until a homogenized solution was achieved

militaris strains were constructed with these two vectors by ATMT method as previous described [26]