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Two hours after administration of the last dose of drugs, mice were observed for sensorimotor function changes

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Chest 105:190194 Svendsen JH, Klarlund K, Aldershvile J, Waldorff S (1989) N-acetylcysteine modifies the acute effects of isosorbide-5-mononitrate in angina pectoris patients evaluated by exercise testing

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In the cytoplasm, a destruction complex comprising adenomatous polyposis coli (APC), AXIN, casein kinase 1 (CK1) and glycogen synthase kinase 3 protein (GSK3 protein) captures -catenin by phosphorylating CK1 and GSK3, thus activating the process of -catenin degradation