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20 , e3012 (2018)

p of Q = 0.976

AMPK phosphorylates NRF2 at the Ser550 residue located in the canonical NES sequence, facilitating NRF2 nuclear accumulation, probably by inhibiting nuclear export [212], and this effect is enhanced by GSK-3 inhibition [213]

In addition, focal radiation strategies such as SRS present a significant risk of distant failure, with new BM arising likely due to residual clusters of tumor cells which were not eliminated by initial radiation treatment