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Ghrelin acts primarily through a GPCR called the GH secretagogue receptor

Although the serum glycerol levels were similarly increased in WT/HFD mice and Insr P1195L/ +/HFD mice, the blood glucose levels after CL316432 administration were significantly higher in Insr P1195L/ +/HFD mice, indicating that enhanced lipolysis exacerbates hyperglycemia in Insr P1195L/ +/HFD mice

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This complex mechanism of cytoskeletal organization dramatically enhances cellular mobility