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a , Immunoblot analysis of SLC33A1 expression from Slc33a1 -knockout KPK cells expressing vector control, WT or mutant SLC33A1 cDNA

NNMT inhibition reduces consumption of nicotinamide (and of S-adenosylmethionine) by blocking the enzyme that would otherwise methylate them

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AOD-9604 therapy should only be pursued under the guidance of a qualified healthcare provider who can determine if this treatment is appropriate for your individual needs and health status.

Cells were gradually frozen in FCS containing10% DMSO at -80C and stored at -150C until they were used for in vitro stimulation assays