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While reshaping our way to connect basic science to clinical needs, we are currently witnessing new trends in drug discovery, sustained by several recent achievements obtained, for instance, in the field of predictive-preventive-personalized-participatory (P4) medicine

For now, it remains a powerful tool for the research community

Some researchers adjust escalation timing based on body weight and individual response, but the target doses themselves remain the same across the research population

Most of these conditions are painful inflammation, fluid accumulation, or require direct medication delivery to the joint or bursa