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In this study, the central mechanism underlying TAM lipid metabolic reprogramming relies on NP-mediated targeted siCB-2 delivery to TAMs, which silences CB-2 expression, disrupts the 2-AG signaling cascade, and redirects TAM polarization toward the pro-inflammatory M1 phenotype, ultimately restoring anti-tumor immune responses

Each tumor-bearing mouse was immobilized in a custom-made Lucite jig, and lead shielding was applied to protect non-tumor areas

Ninjurin-1 (NINJ1), a protein that plays a key role in pyroptosis, was recently found to undergo oligomerization during ferroptosis

Copper peptides stimulate collagen production and help reinforce the skin barrier, making them ideal for reducing crow's feet and restoring elasticity