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verbal learning, memory, and processing speed, and deficits often persists after mood symptom remission [31,32,33,34]

Tetrandrine suppresses Wnt/-catenin activity by preventing -catenin nuclear translocation, reducing Wnt3a levels, and modulating key downstream targets like CyclinD1 and c-Myc

Acute oral toxicity tests in rats indicated safety at doses up to 2,000 mg/kg, with no harm observed on A

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Codon reassignment Synonymous codon compression, followed by the removal of all tRNAs that read the deleted codon may allow the codon to be reassigned using orthogonal aminoacyl-tRNA synthetase/tRNA pairs