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doi: 10.3389/fpubh.2024.1425023 Received 29 April 2024 Accepted 18 July 2024 Published 09 August 2024 Volume 12 - 2024 Edited by Damir B

However, tumor cells in the TME can produce Arg1, which breaks down extracellular arginine outside of T cells, leading to a deficiency of arginine and inhibiting T cell function

J Invest Dermatol 1995

Pioneer studies assessing the effect of enteral supplement with glutamine granules on intestinal IEB function in severely burned patients, showed that this compound can improve intestinal mucosal permeability, decrease plasma endotoxin levels, reduce hospital stay and costs (353, 354)