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For example, it remains unclear how Mtb spatiotemporally regulates the intra- and extranuclear functions of these nucleus-translocated effectors

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These downstream signaling events in SCs can be significantly suppressed by restricting ROS specifically in HCs, supporting the notion that EGFR in SCs serves as a receptor for oxidative stress recognition

In some instances, it is possible that these nutrients, per se, may not be required to promote tumor growth on their own, but the by-products of their metabolism may instead contribute an essential component to tumor maintenance

COPD, chronic obstructive pulmonary disease